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Principal Scientist

Principal Scientist


An exceptional opportunity for a Principal Scientist to join a Biotechnology start-up in Oxford who are using “deep phenotyping” to develop treatments for Chronic Liver Disease (one of the top ten causes of global deaths). You will be joining a company that have experienced huge success and are now going into growth mode to help develop and optimise their technology and ultimate save more patients’ lives.
We are seeking talented and motivated scientists who are ambitious and want to be part of a truly inspirational journey of growth and innovation. This is an opportunity to really impact one of the most pressing healthcare challenges of our time.
Principal Scientist
Salary: Up to £70,000 (DOE) + Package (35 days holiday, IT Allowance, 6.5% pension, stock options)
Location: Oxford
Responsibilities include:

  • To execute on the in vitro and ex vivo programmes at Ochre Bio.
  • Lead projects including mentoring/management of junior scientists
  • Develop new technologies/pipelines that work towards our overall aims but our current focus includes:
    • Target validation in complex primary cell models of cellular and metabolic stress
    • Mechanism of action studies using RNAseq and drug interactions
    • Lead development of our siRNA therapeutics
  • To assist the scientific team to assemble the data packages for our lead therapies as we move into our next round of funding.
  • To help with the smooth running of the lab (good record keeping, tidiness, teamwork)
  • Whilst not needed for this post, learning and developing expertise in R-based data analysis will be a requirement for future progression, and will be actively encouraged.

Desirable Skills:

  • PhD in a relevant Field 
  • Experience with cellular models using sterile technique
  • Experience of working with primary cell
  • Experience in metabolism or R-based data analysis (not essential)
  • Experience in a fast-paced, value-based innovation environment

Please apply today and we will contact you with more information.

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Job Overview
Science & Biotechnology
Offered Salary
Job Location